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pentobarbital decreases levels of elvitegravir/cobicistat/emtricitabine/tenofovir DF by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. May well lead to loss of virologic response and doable resistance.It may also use sedatives and muscle relaxants, a drug to decelerate the guts, and an anti-epileptic to forestall seizure an